This domain is found in uncharacterised proteins predominantly from bacteria. It contains two pairs of conserved cysteine residues that may be involved in metal ion coordination. This domain is predicted to adopt a fold typical for zinc beta-ribbon domains.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0167","name":"Zn_Beta_Ribbon"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":3,"interactions":0,"matches":50,"pathways":0,"proteins":50,"proteomes":48,"sets":1,"structural_models":{"alphafold":37},"structures":0,"taxa":186},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":19,"alignment:full":30},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}