This domain is found in uncharacterised proteins. It contains two pairs of highly conserved cysteine residues that may coordinate a metal ion. This domain is predicted to fold into a structure that is probably distantly related to domains with beta-tent fold (CL0080). The zinc ribbon in this domain is grafted into alpha/beta core.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0167","name":"Zn_Beta_Ribbon"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":4,"interactions":0,"matches":334,"pathways":0,"proteins":334,"proteomes":267,"sets":1,"structural_models":{"alphafold":255},"structures":0,"taxa":646},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":26,"alignment:full":210},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}