{"metadata":{"accession":"PF26721","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR059285","hierarchy":null,"name":{"name":"Domain of unknown function (DUF8241)","short":"DUF8241"},"description":[{"text":"<p>This domain is found in uncharacterised plant proteins. It contains three repeats with topology similar to the C-terminal domain of defensin. Each of these repeats has two predicted disulfide bonds that are conserved and occupying the same spatial position as the disulfide bonds in defensin. This domain is frequently found in combination with [pfam:PF23106] and [pfam:PF13920].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0075","name":"Defensin"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":7,"interactions":0,"matches":48,"pathways":0,"proteins":46,"proteomes":41,"sets":1,"structural_models":{"alphafold":39},"structures":0,"taxa":107},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":25,"alignment:full":37},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}