This domain is found in uncharacterised proteins from Gram-negative bacteria. It is predicted to fold into a beta-sandwich which has some similarity to known carbohydrate binding domains. It is frequently found in combination with [pfam:PF07589] PEP-CTERM sorting motif suggesting that it may be associated with the membrane.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0004","name":"Concanavalin"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":3,"interactions":0,"matches":65,"pathways":0,"proteins":63,"proteomes":61,"sets":1,"structural_models":{"alphafold":44},"structures":0,"taxa":136},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":31,"alignment:full":44},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}