This domain is found in uncharacterised bacterial proteins. It is predicted to fold into a globular structure with significant similarity to C-type lectin. Compared to known C-type lectin domains this domain contains a large insertion comprising a six-stranded beta-meander. Some proteins contain two copies of this domain.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0056","name":"C_Lectin"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":15,"interactions":0,"matches":132,"pathways":0,"proteins":131,"proteomes":67,"sets":1,"structural_models":{"alphafold":90},"structures":0,"taxa":155},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":29,"alignment:full":119},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}