This entry represents a domain from a family of uncharacterised proteins predominantly found in the bacterial phylum Thermodesulfobacteriota. The proteins containing this domain are mainly distributed among the orders Desulfovibrionales and Desulfobacterales. The domain is approximately 85 amino acids in length. Proteins containing this domain are predicted to be involved in various cellular processes, but their exact function remains unknown. The domain is sometimes associated with the [pfam:PF11823] domain, which is a putative Se/S carrier protein-like domain. This domain shows structure similarity to the N-terminal domain of Enolase.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0227","name":"Enolase_N"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":103,"pathways":0,"proteins":103,"proteomes":102,"sets":1,"structural_models":{"alphafold":91},"structures":0,"taxa":270},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":14,"alignment:full":72},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}