This entry represents an NTF2 superfamily domain found in a family of uncharacterised proteins from the Actinomycetota phylum, specifically within the Actinomycetes class. The family is predominantly found in Streptomycetaceae and Nocardiaceae families, with a notable presence in Streptomyces species. Proteins in this family are typically around 250-300 amino acids in length. Many members contain predicted transmembrane helices, suggesting they may be integral membrane proteins.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0051","name":"NTF2"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":1834,"pathways":0,"proteins":1832,"proteomes":1257,"sets":1,"structural_models":{"alphafold":972},"structures":0,"taxa":1587},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":93,"alignment:full":850},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}