This entry represents a domain from a family of uncharacterised proteins predominantly found in the Mycobacteriaceae family. The proteins in this family are primarily distributed across various species of Mycobacterium and Mycolicibacterium. The domain is typically found in proteins ranging from approximately 160 to 230 amino acids in length. Many of these proteins are predicted to be membrane-associated, as suggested by the presence of transmembrane helices. The precise function of this domain remains unknown. This domain belongs to the NTF2 superfamily.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0051","name":"NTF2"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":226,"pathways":0,"proteins":226,"proteomes":226,"sets":1,"structural_models":{"alphafold":176},"structures":0,"taxa":256},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":52,"alignment:full":81},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}