This entry represents a pair of domains from a family of uncharacterised proteins in halophilic archaea. The proteins are predominantly found in the class Halobacteria, which includes genera such as Halorubrum, Natrialbaceae, and Haloferacaceae. The proteins in this family typically range from 180 to 270 amino acids in length. The family contains one domain nested withing another. The outer domain shows structural similarity to [pfam:PF05014] a family of Nucleoside 2-deoxyribosyltransferases.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0498","name":"Nribosyltransf"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":289,"pathways":0,"proteins":289,"proteomes":183,"sets":1,"structural_models":{"alphafold":272},"structures":0,"taxa":307},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":6,"alignment:full":119},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}