{"metadata":{"accession":"PF26498","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR058478","hierarchy":null,"name":{"name":"Domain of unknown function (DUF8164)","short":"DUF8164"},"description":[{"text":"<p>This entry represents a family of uncharacterised proteins from halophilic archaea. The proteins are primarily found in members of the Halobacteria class, including genera such as Natrialba, Natrarchaeobaculum, and Halobiforma. The proteins in this family typically range from 200 to 300 amino acids in length. These proteins contain an Ig-like fold.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0159","name":"E-set"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":37,"pathways":0,"proteins":37,"proteomes":37,"sets":1,"structural_models":{"alphafold":33},"structures":0,"taxa":100},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":11,"alignment:full":18},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}