{"metadata":{"accession":"PF26488","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR058471","hierarchy":null,"name":{"name":"Domain of unknown function (DUF8158)","short":"DUF8158"},"description":[{"text":"<p>This entry represents a domain from a family of uncharacterised proteins in Halobacteria. The proteins containing this domain are primarily found in various genera within the Halobacteriales order, including Halorubrum, Haloarculaceae, and Haloferacaceae. The domain is approximately 109 amino acids in length. The domain is composed of four alpha helices.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":99,"pathways":0,"proteins":99,"proteomes":79,"sets":0,"structural_models":{"alphafold":93},"structures":0,"taxa":146},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":11,"alignment:full":34},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}