This entry represents a C-terminal region from a family of uncharacterised proteins from halophilic archaea. The proteins in this family are predominantly found in the class Halobacteria, which includes families such as Haloferacaceae, Natrialbaceae, and Haloarculaceae. The proteins in this family are approximately 130-150 amino acids in length. This region is often associated with an N-terminal RHH domain.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":278,"pathways":0,"proteins":278,"proteomes":278,"sets":0,"structural_models":{"alphafold":265},"structures":0,"taxa":434},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":45,"alignment:full":124},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}