This entry represents a family of uncharacterised proteins in archaea. The proteins are predominantly found in the class Halobacteria, which includes families such as Natrialbaceae, Haloferacaceae, and Haloarculaceae. This family contains proteins ranging from 50 to 115 amino acids in length. These proteins contain and N-terminal transmembrane helix followed by a likely disordered C-terminus.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
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