{"metadata":{"accession":"PF26459","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR058451","hierarchy":null,"name":{"name":"Family of unknown function (DUF8138)","short":"DUF8138"},"description":[{"text":"<p>This entry represents a family of uncharacterised proteins from archaea. The proteins in this family are predominantly found in the order Halobacteriales, which includes genera such as Natrinema and Halostagnicola. The proteins are relatively short, typically ranging from 74 to 114 amino acids in length.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":42,"pathways":0,"proteins":42,"proteomes":42,"sets":0,"structural_models":{"alphafold":42},"structures":0,"taxa":105},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":6,"alignment:full":15},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}