This entry represents a domain from a family of uncharacterised proteins in archaea. The proteins are predominantly found in the Halobacteria class, including genera such as Halogeometricum and Haloplanus. The proteins in this family are typically around 67 to 84 amino acids in length. These proteins are predicted to be integral membrane proteins with two transmembrane helices.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":46,"pathways":0,"proteins":46,"proteomes":46,"sets":0,"structural_models":{"alphafold":42},"structures":0,"taxa":77},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":4,"alignment:full":14},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}