This entry represents a small alpha helical domain from a family of uncharacterised proteins in halobacteria. The domain is found in proteins from various archaea, particularly within the Halobacteriales order. The proteins containing this domain are typically around 70 to 80 amino acids in length. The domain shows a high degree of conservation across different species within the Halobacteriales, suggesting a potentially important but yet unidentified role.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
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