This entry represents an alpha-helical domain from a family of uncharacterised proteins in the Halobacteria class of Archaea. The proteins containing this domain are predominantly found in members of the Haloferacaceae family, including genera such as Halonotius, Halobellus, and Halorubrum. The domain is typically found in proteins ranging from 209 to 263 amino acids in length.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":92,"pathways":0,"proteins":90,"proteomes":89,"sets":0,"structural_models":{"alphafold":86},"structures":0,"taxa":137},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":13,"alignment:full":34},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}