This entry represents a domain from a family of uncharacterised proteins found predominantly in the class Halobacteria within the Archaea domain. The proteins containing this domain are primarily distributed among various genera such as Halorubrum, Halalkalicoccus, and Natronococcus. The domain is typically found in proteins ranging from 90 to 250 amino acids in length. These domains contain to CXXC motifs suggesting they are zinc binding domains.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":131,"pathways":0,"proteins":131,"proteomes":80,"sets":0,"structural_models":{"alphafold":120},"structures":0,"taxa":152},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":27,"alignment:full":55},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}