This entry represents a domain from a family of uncharacterised proteins predominantly found in halophilic archaea. The proteins in this family are primarily distributed among the Halobacteria class, including genera such as Natronomonas and Haloarcula. Additionally, some members are found in viruses infecting these archaea. The proteins are relatively short, with lengths ranging from approximately 113 to 131 amino acids.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
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