This entry represents a family of uncharacterised proteins in archaea. The proteins containing this domain are predominantly found in the class Halobacteria, which are known for their adaptation to high-salt environments. The proteins in this family are typically around 100 to 300 amino acids in length. Many of these proteins are predicted to be integral membrane proteins, as suggested by the presence of multiple transmembrane helices. The family contains a C-terminal zinc ribbon domain.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0167","name":"Zn_Beta_Ribbon"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":10,"interactions":0,"matches":265,"pathways":0,"proteins":265,"proteomes":170,"sets":1,"structural_models":{"alphafold":246},"structures":0,"taxa":283},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":72,"alignment:full":100},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}