{"metadata":{"accession":"PF26408","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR058419","hierarchy":null,"name":{"name":"Domain of unknown function (DUF8106)","short":"DUF8106"},"description":[{"text":"<p>This entry represents a domain from a family of uncharacterised domain in the Halobacteria class of Archaea. The proteins in this family are predominantly found in various families within the Halobacteriales order, including Natrialbaceae, Haloferacaceae, and Haloarculaceae. The domain is typically found in proteins ranging from 58 to 130 amino acids in length. A reviewed protein containing this domain is found in Haloferax volcanii ([swissprot:D4GSN3]). This domain contains two CXXC motifs suggesting it is likely to be zinc binding.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0167","name":"Zn_Beta_Ribbon"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":3,"interactions":0,"matches":292,"pathways":0,"proteins":292,"proteomes":222,"sets":1,"structural_models":{"alphafold":268},"structures":0,"taxa":354},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":20,"alignment:full":108},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}