This entry represents a domain from a family of uncharacterised proteins in halobacteria. The proteins in this family are predominantly found in archaea, specifically within the Halobacteria class. The taxonomic distribution includes genera such as Halorubrum, Haloquadratum, and Haloarcula, among others. The proteins in this family are typically around 116 to 118 amino acids in length. Some proteins in this family are associated with plasmids, suggesting potential roles in horizontal gene transfer or adaptation. The subcellular localization of these proteins is not well-defined, but they may contain zinc finger-like motifs, indicating potential roles in nucleic acid binding or protein-protein interactions.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
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