This entry represents a domain from a family of uncharacterised proteins in archaea. The proteins in this family are predominantly found in the class Halobacteria, which includes organisms such as Haloferacaceae and Halobacteriales. The proteins in this family typically range from 124 to 143 amino acids in length. Many proteins in this family contain predicted coiled-coil regions.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":57,"pathways":0,"proteins":57,"proteomes":56,"sets":0,"structural_models":{"alphafold":49},"structures":0,"taxa":131},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":10,"alignment:full":20},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}