{"metadata":{"accession":"PF26357","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR058405","hierarchy":null,"name":{"name":"Domain of unknown function (DUF8092)","short":"DUF8092"},"description":[{"text":"<p>This entry represents a domain of unknown function (DUF8092) found exclusively in members of the Mycobacterium tuberculosis complex. The domain is approximately 54 amino acids in length and is highly conserved across all known members. The function of this domain has not been experimentally determined.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":7,"pathways":0,"proteins":7,"proteomes":7,"sets":0,"structural_models":{"alphafold":4},"structures":0,"taxa":19},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":4,"alignment:full":4},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}