This entry represents a family of uncharacterised proteins. One of these is ORFg found in retron Ec67.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00011664":{"PMID":1701261,"ISBN":null,"volume":"87","issue":"23","year":1990,"title":"Retron for the 67-base multicopy single-stranded DNA from Escherichia coli: a potential transposable element encoding both reverse transcriptase and Dam methylase functions.","URL":null,"raw_pages":"9454-8","medline_journal":"Proc Natl Acad Sci U S A","ISO_journal":"Proc. Natl. Acad. Sci. U.S.A.","authors":["Hsu MY","Inouye M","Inouye S."],"DOI_URL":"http://www.pubmedcentral.nih.gov/picrender.fcgi?tool=EBI&pubmedid=1701261&action=stream&blobtype=pdf"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":17,"pathways":0,"proteins":17,"proteomes":15,"sets":0,"structural_models":{"alphafold":11},"structures":0,"taxa":68},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":4,"alignment:full":6},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}