{"metadata":{"accession":"PF25824","entry_id":null,"type":"repeat","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR057711","hierarchy":null,"name":{"name":"Repeat of unknown function (DUF7951)","short":"DUF7951"},"description":[{"text":"<p>This entry describes a repeat of unknown function found at the C-terminal of uncharacterised proteins mainly from animals. It displays a TPR fold.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00035836":{"PMID":15590835,"ISBN":null,"volume":"3","issue":"6","year":2004,"title":"The small-subunit processome is a ribosome assembly intermediate.","URL":null,"raw_pages":"1619-26","medline_journal":"Eukaryot Cell","ISO_journal":"Eukaryotic Cell","authors":["Bernstein KA","Gallagher JE","Mitchell BM","Granneman S","Baserga SJ."],"DOI_URL":"http://dx.doi.org/10.1128/EC.3.6.1619-1626.2004"}},"set_info":{"accession":"CL0020","name":"TPR"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":11,"interactions":0,"matches":75,"pathways":0,"proteins":75,"proteomes":65,"sets":1,"structural_models":{"alphafold":69},"structures":0,"taxa":166},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":11,"alignment:full":60},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}