{"metadata":{"accession":"PF25313","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR057451","hierarchy":null,"name":{"name":"BRWD/PHIP ancillary domain-like domain","short":"BRWD_AD"},"description":[{"text":"<p>This entry represents a conserved domain found in bromodomain and WD repeat-containing proteins (BRWD) and PH-interacting protein (PHIP). The domain shows structural similarity to the ancillary domain of Auxin Response Factors ([pfam:PF06507]). It is found in BRWD1, BRWD3 and PHIP proteins, which are involved in transcriptional regulation. BRWD1 and BRWD3 proteins contain multiple bromodomains and WD40 repeats, while PHIP contains WD40 repeats and a PH domain.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":null,"set_info":{"accession":"CL0893","name":"AD"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":177,"interactions":0,"matches":6183,"pathways":0,"proteins":6152,"proteomes":1610,"sets":1,"structural_models":{"alphafold":679,"bfvd":0},"structures":0,"taxa":5318},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":29,"alignment:full":4299},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}