{"metadata":{"accession":"PF25276","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR057192","hierarchy":null,"name":{"name":"Domain of unknown function (DUF7870)","short":"DUF7870"},"description":[{"text":"<p>This domain is found in uncharacterised plant proteins. It has detectable similarity to methyltransferases and it is predicted to adopt similar structure. It contains two highly conserved cysteines and a histidine.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0063","name":"NADP_Rossmann"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":50,"interactions":0,"matches":3215,"pathways":0,"proteins":2300,"proteomes":378,"sets":1,"structural_models":{"alphafold":1849},"structures":0,"taxa":1082},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":70,"alignment:full":2003},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}