This entry represents a conserved domain of unknown function (DUF7678) found in various bacterial species. The domain is approximately 75-100 amino acids in length and contains several highly conserved residues. The function of this domain remains to be determined. Structure prediction suggests this domain is composed of a 6 stranded beta sheet with an Alpha helix packed on one side.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":146,"pathways":0,"proteins":146,"proteomes":128,"sets":0,"structural_models":{"alphafold":96},"structures":0,"taxa":334},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":64,"alignment:full":137},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}