{"metadata":{"accession":"PF24593","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR055388","hierarchy":null,"name":{"name":"Domain of unknown function (DUF7617)","short":"DUF7617"},"description":[{"text":"<p>This domain is found in multiple copies in a number of bacterial proteins mainly from Actinomycetales. It is closely related to domains represented by [pfam:PF01345] and [pfam:PF24346]. Similarly to them, this domain contains a conserved N-terminal lysine and a C-terminal asparagine with central aspartate/glutamate residues suggesting that some members may contain an isopeptide bond. This domain is sometimes found in combination with [pfam:PF01345] or [pfam:PF24346].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0159","name":"E-set"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":15,"interactions":0,"matches":190,"pathways":0,"proteins":120,"proteomes":95,"sets":1,"structural_models":{"alphafold":67},"structures":0,"taxa":148},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":18,"alignment:full":90},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}