This entry represents a small family of uncharacterised proteins from a set of mycobacterial phage including phage Bxb1 (gene 86). The members of the family range in length from 50 to 90 residues. Structurally, the domain shows some weak similarity to the N-terminal domain of IF5, which adopts an SH3 like barrel fold.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0010","name":"SH3"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":14,"pathways":0,"proteins":14,"proteomes":14,"sets":1,"structural_models":{"alphafold":1},"structures":0,"taxa":37},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":4,"alignment:full":31},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}