{"metadata":{"accession":"PF24251","entry_id":null,"type":"repeat","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR055876","hierarchy":null,"name":{"name":"Family of unknown function (DUF7453)","short":"DUF7453"},"description":[{"text":"<p>This entry represents a group of uncharacterised sequences from bacteria. According to structure predictions, these proteins may comprise novel repeats consisting of an arrangement of four beta-strands in which the second one is longer and curved. This arrangement is repeated eight times in SwissProt:A0A5B9QB27, which form a closed repeat.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0186","name":"Beta_propeller"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":18,"interactions":0,"matches":258,"pathways":0,"proteins":200,"proteomes":104,"sets":1,"structural_models":{"alphafold":155},"structures":0,"taxa":305},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":11,"alignment:full":243},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}