This entry represents an uncharacterized protein family found in bacteriophages. The function of this family is currently unknown. Members of this family are typically around 90-100 amino acids in length. The family includes proteins from various phage species infecting bacteria such as Salmonella, Klebsiella, and Proteus. Some members of this family contain disordered regions, particularly in their C-terminal portions. Conserved basic and acidic residues are present in many family members, which may be functionally important. This entry represents the globular N-terminal domain of these proteins.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
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