This domain is found C-terminal in uncharacterised bacterial proteins. It is predicted to adopt a seven-stranded antiparallel beta-sheet with similarity to Mog1p/PsbP-like domains. Some proteins containing this domain have a lipoprotein attachment motif at the N-terminus suggesting they may be associated with the membrane. This domain is usually found in two copies that share little if any sequence similarity to each other.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0619","name":"Mog1p_PsbP"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":5,"interactions":0,"matches":1002,"pathways":0,"proteins":1002,"proteomes":289,"sets":1,"structural_models":{"alphafold":637},"structures":0,"taxa":356},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":59,"alignment:full":368},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}