This entry represents an uncharacterized protein of approximately 54 amino acids found in T5-like bacteriophages that infect Escherichia coli and Salmonella. Homologs have been identified in several T5-like phages including bacteriophage T5, Salmonella phage vB_SenS_SB13, and Escherichia phage vB_EcoS-26175V. Structure prediction suggests that this protein forms a strand swapped homodimeric arrangement. The dimeric structure forms two four stranded sheets that are connected by two alpha helices. The C-terminal of each protein is donated to the sheet made by the other monomer.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":123,"pathways":0,"proteins":123,"proteomes":122,"sets":0,"structural_models":{"alphafold":1},"structures":0,"taxa":256},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":2,"alignment:full":12},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}