This entry represents a domain of unknown function, which is found in phage proteins, predominantly from Arthrobacter and Gordonia phages. The domain is approximately 110 amino acids in length. It shows similarity to the Phage_barrel superfamily. These proteins are often components of the phage neck complex.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0504","name":"Phage_barrel"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":66,"pathways":0,"proteins":66,"proteomes":65,"sets":1,"structural_models":{"alphafold":12},"structures":0,"taxa":175},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":24,"alignment:full":54},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}