This entry represents an uncharacterized protein found in various bacteriophages that infect bacteria in the family Enterobacteriaceae, including phages of Escherichia, Shigella and Citrobacter. The protein is approximately 55-60 amino acids in length. An AlphaFold model shows this domain adopts a small beta barrel structure. This domain is possibly related to the KOW motif.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0010","name":"SH3"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":62,"pathways":0,"proteins":62,"proteomes":62,"sets":1,"structural_models":{"alphafold":4},"structures":0,"taxa":169},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":11,"alignment:full":41},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}