This entry represents an uncharacterized protein family found in various phages infecting Gram-negative bacterial hosts, including Salmonella, Shigella, Erwinia, Aeromonas, Vibrio and Klebsiella phages. The family typically contains proteins between 80-120 amino acids in length. The function of this protein family is currently unknown.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":43,"pathways":0,"proteins":43,"proteomes":43,"sets":0,"structural_models":{"alphafold":3},"structures":0,"taxa":108},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":6,"alignment:full":11},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}