{"metadata":{"accession":"PF23638","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR055569","hierarchy":null,"name":{"name":"Domain of unknown function (DUF7145)","short":"DUF7145"},"description":[{"text":"<p>This entry represents a domain of unknown function found in Trichuris sp., Trichinella sp. and similar sequences from nematodes. This domain is repeated in some sequences from Trichuris spp. (two to four times) and it  may adopt a SH2-like fold.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0541","name":"SH2-like"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":13,"interactions":0,"matches":143,"pathways":0,"proteins":76,"proteomes":15,"sets":1,"structural_models":{"alphafold":61},"structures":0,"taxa":34},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":3,"alignment:full":122},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}