{"metadata":{"accession":"PF23398","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR056614","hierarchy":null,"name":{"name":"FAZ1, conserved domain","short":"FAZ1_cons"},"description":[{"text":"<p>This entry represents a conserved repeated domain found twice in FAZ1 from Trypanosoma brucei and similar sequences from trypanosomatids [[cite:PUB00155625]]. This domain is found near the central region and at the very C-terminal of FAZ1. At least 50%  of the T. cruzi genome is repetitive sequence, consisting mostly of large gene families of surface proteins, retrotransposons, and subtelomeric repeats [[cite:PUB00155626]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00155625":{"PMID":17945531,"ISBN":null,"volume":"159","issue":"1","year":2008,"title":"A repetitive protein essential for the flagellum attachment zone filament structure and function in Trypanosoma brucei.","URL":null,"raw_pages":"127-36","medline_journal":"Protist","ISO_journal":"Protist","authors":["Vaughan S","Kohl L","Ngai I","Wheeler RJ","Gull K."],"DOI_URL":"https://doi.org/10.1016/j.protis.2007.08.005"},"PUB00155626":{"PMID":1112631,"ISBN":null,"volume":"5","issue":"1","year":1975,"title":"[Experimental trichinosis-I. The course of delayed hypersensitivity in the CBA mouse and Wistar rat (author's transl)].","URL":null,"raw_pages":"63-70","medline_journal":"Int J Parasitol","ISO_journal":"Int J Parasitol","authors":["Vernes A","Floc'h F","Biguet J","Tailliez R."],"DOI_URL":"https://doi.org/10.1016/0020-7519(75)90099-5"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":70,"interactions":0,"matches":1449,"pathways":0,"proteins":569,"proteomes":30,"sets":0,"structural_models":{"alphafold":347},"structures":0,"taxa":73},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":68,"alignment:full":892},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}