This entry includes uncharacterised fungal sequences which consist of repeats that may adopt an alpha-solenoid structure related to ankirin repeats. The overall arrangement of these repeats may have a horseshoe conformation similar to that in leucine-rich repeats.
","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"A domain of unknown function (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.
","thumbnail":null}],"literature":{"PUB00155612":{"PMID":27150427,"ISBN":null,"volume":"7","issue":null,"year":2016,"title":"Survival trade-offs in plant roots during colonization by closely related beneficial and pathogenic fungi.","URL":null,"raw_pages":"11362","medline_journal":"Nat Commun","ISO_journal":"Nat Commun","authors":["Hacquard S","Kracher B","Hiruma K","Munch PC","Garrido-Oter R","Thon MR","Weimann A","Damm U","Dallery JF","Hainaut M","Henrissat B","Lespinet O","Sacristan S","Ver Loren van Themaat E","Kemen E","McHardy AC","Schulze-Lefert P","O'Connell RJ."],"DOI_URL":"https://doi.org/10.1038/ncomms11362"},"PUB00155611":{"PMID":27387256,"ISBN":null,"volume":"18","issue":"11","year":2016,"title":"Effector profiles distinguish formae speciales of Fusarium oxysporum.","URL":null,"raw_pages":"4087-4102","medline_journal":"Environ Microbiol","ISO_journal":"Environ Microbiol","authors":["van Dam P","Fokkens L","Schmidt SM","Linmans JH","Kistler HC","Ma LJ","Rep M."],"DOI_URL":"https://doi.org/10.1111/1462-2920.13445"}},"set_info":{"accession":"CL0465","name":"Ank"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":465,"interactions":0,"matches":8146,"pathways":0,"proteins":1355,"proteomes":441,"sets":1,"structural_models":{"alphafold":848},"structures":0,"taxa":904},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":206,"alignment:full":6585},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}