{"metadata":{"accession":"PF23396","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR055529","hierarchy":null,"name":{"name":"Family of unknown function (DUF7103)","short":"DUF7103"},"description":[{"text":"<p>This is a family of unknown function. It is structurally similar to Frag1-like domain, composed of a six-alpha-helix bundle transmembrane region [[cite:PUB00155610]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":{"PUB00155610":{"PMID":37704730,"ISBN":null,"volume":"622","issue":"7983","year":2023,"title":"Clustering predicted structures at the scale of the known protein universe.","URL":null,"raw_pages":"637-645","medline_journal":"Nature","ISO_journal":"Nature","authors":["Barrio-Hernandez I","Yeo J","Janes J","Mirdita M","Gilchrist CLM","Wein T","Varadi M","Velankar S","Beltrao P","Steinegger M."],"DOI_URL":"https://doi.org/10.1038/s41586-023-06510-w"}},"set_info":{"accession":"CL0412","name":"Frag1-like"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":23,"pathways":0,"proteins":23,"proteomes":23,"sets":1,"structural_models":{"alphafold":10},"structures":0,"taxa":65},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":6,"alignment:full":12},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}