{"metadata":{"accession":"PF23392","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR055527","hierarchy":null,"name":{"name":"Domain of unknown function (DUF7101)","short":"DUF7101"},"description":[{"text":"<p>This is a domain found in a group on uncharacterised proteins from fungi. The function of this domain is unknown. According to structural predictions, this domain likely adopts an alpha-beta-beta-beta-beta-alpha fold. This domain is usually found associated with an alpha-helical domain at the N-terminal ([pfam:PF23391]) and a beta-propeller at the C-terminal ([pfam:PF23388]).</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":8,"interactions":0,"matches":145,"pathways":0,"proteins":144,"proteomes":140,"sets":0,"structural_models":{"alphafold":118},"structures":0,"taxa":317},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":28,"alignment:full":115},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}