{"metadata":{"accession":"PF22511","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR054264","hierarchy":null,"name":{"name":"PolB1 Binding Protein 2","short":"PBP2"},"description":[{"text":"<p>This is a family of archaeal proteins, previously known as DUF6995, representing homologues of PolB1 Binding Protein 2 (PBP2). PBP2, is a subunit of PolB1 enzyme that is a member of the archaeal B-family of DNA polymerases. PBP2 along with PBP1, associate with distinct surfaces of the larger catalytic subunit and influence the enzymatic properties of the DNA polymerase [[cite:PUB00154412]]. Members of this family adopt a winged helix (HTH) fold.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00154412":{"PMID":28462924,"ISBN":null,"volume":"8","issue":null,"year":2017,"title":"Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme.","URL":null,"raw_pages":"15075","medline_journal":"Nat Commun","ISO_journal":"Nat Commun","authors":["Yan J","Beattie TR","Rojas AL","Schermerhorn K","Gristwood T","Trinidad JC","Albers SV","Roversi P","Gardner AF","Abrescia NGA","Bell SD."],"DOI_URL":"https://doi.org/10.1038/ncomms15075"}},"set_info":{"accession":"CL0123","name":"HTH"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":56,"pathways":0,"proteins":56,"proteomes":54,"sets":1,"structural_models":{"alphafold":55},"structures":2,"taxa":130},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":26,"alignment:full":35},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":{"accession":"5n41","name":"Archaeal DNA polymerase holoenzyme - SSO6202 at 1.35 Ang resolution"}}}