{"metadata":{"accession":"PF22285","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR054235","hierarchy":null,"name":{"name":"Family of unknown function (DUF6962)","short":"DUF6962"},"description":[{"text":"<p>This is a family of uncharacterised bacterial proteins. They are related to HlyIII family [pfam:PF03006] and are predicted to adopt the same structure consisting of seven transmembrane helices. Their predicted structure, suggests that, similarly to HlyIII, they may contain a Zn-binding site, albeit slightly rearranged as only two of the Zn-coordinating residues are in conserved positions.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0192","name":"GPCR_A"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":6,"interactions":0,"matches":392,"pathways":0,"proteins":390,"proteomes":366,"sets":1,"structural_models":{"alphafold":281},"structures":0,"taxa":769},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":73,"alignment:full":214},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}