{"metadata":{"accession":"PF21818","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR049251","hierarchy":null,"name":{"name":"Family of unknown function (DUF6884)","short":"DUF6884"},"description":[{"text":"<p>This is a domain of unknown function that is found either as a standalone protein or in combination with other domains. Members of this family possess a highly conserved LSAXXG motif that may constitute an active site. This domain may be distantly related to oxidative stress response YaaA proteins.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0771","name":"UDG-like"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":21,"interactions":0,"matches":1085,"pathways":0,"proteins":1085,"proteomes":989,"sets":1,"structural_models":{"alphafold":737},"structures":0,"taxa":1965},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":57,"alignment:full":529},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}