{"metadata":{"accession":"PF20680","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR049202","hierarchy":null,"name":{"name":"Domain of unknown function (DUF6817)","short":"DUF6817"},"description":[{"text":"<p>This presumed domain is functionally uncharacterised, found in bacteria and plants. It is approximately 160 amino acids in length and it has two conserved sequence motifs, HL and GLxHxxY. Several members of this entry also has TPR regions.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0237","name":"HD_PDEase"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":38,"interactions":0,"matches":1461,"pathways":0,"proteins":1456,"proteomes":1125,"sets":1,"structural_models":{"alphafold":980},"structures":0,"taxa":2346},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":88,"alignment:full":773},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}