{"metadata":{"accession":"PF20581","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR046712","hierarchy":null,"name":{"name":"Family of unknown function (DUF6785)","short":"DUF6785"},"description":[{"text":"<p>This family of proteins is functionally uncharacterised. This family of proteins is found in bacteria and archaea. There are highly conserved sequence motifs: FSxWFF and ExxxFP. There are eleven conserved tryptophan residues, which may suggest to play an important role. Proteins members of this family are likely composed of transmembrane helices and probably carry out transporter activity.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":[{"title":"Domain_of_unknown_function","extract":"<p>A <b>domain of unknown function</b> (DUF) is a protein domain that has no characterised function. These families have been collected together in the Pfam database using the prefix DUF followed by a number, with examples being DUF2992 and DUF1220. As of 2019, there are almost 4,000 DUF families within the Pfam database representing over 22% of known families. Some DUFs are not named using the nomenclature due to popular usage but are nevertheless DUFs.</p>","thumbnail":null}],"literature":null,"set_info":{"accession":"CL0962","name":"YS1_YSL"},"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":2,"interactions":0,"matches":148,"pathways":0,"proteins":136,"proteomes":72,"sets":1,"structural_models":{"alphafold":100},"structures":0,"taxa":238},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":65,"alignment:full":107},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}