{"metadata":{"accession":"PF20381","entry_id":null,"type":"family","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR046498","hierarchy":null,"name":{"name":"Membrane protein Rv1476","short":"Rv1476"},"description":[{"text":"<p>This entry, previously known as DUF6676, represents Membrane protein Rv1476 an related proteins found in actinobacteria. Rv1476 probably affects the expression of genes linked to host macrophage apoptosis and immune response, thereby promoting the survival of Mycobacterium tuberculosis in host macrophages [[cite:PUB00155435]].</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00155435":{"PMID":38392218,"ISBN":null,"volume":"46","issue":"2","year":2024,"title":"The Role of Rv1476 in Regulating Stress Response and Intracellular Survival of <i>Mycobacterium tuberculosis</i>.","URL":null,"raw_pages":"1556-1566","medline_journal":"Curr Issues Mol Biol","ISO_journal":"Curr Issues Mol Biol","authors":["Reheman A","Wang Y","Cai H","Wei P","Cao G","Chen X."],"DOI_URL":"https://doi.org/10.3390/cimb46020100"}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":1,"interactions":0,"matches":628,"pathways":0,"proteins":628,"proteomes":627,"sets":0,"structural_models":{"alphafold":411},"structures":0,"taxa":746},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":73,"alignment:full":249},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}