{"metadata":{"accession":"PF20254","entry_id":null,"type":"domain","go_terms":null,"source_database":"pfam","member_databases":null,"integrated":"IPR046540","hierarchy":null,"name":{"name":"N,N-dimethylformamidase beta subunit-like, C-terminal","short":"DMFA2_C"},"description":[{"text":"<p>This entry represents a domain found at the C-terminal of bacterial proteins, including N,N-dimethylformamidase beta (DMFA2) subunit from Paracoccus [[cite:PUB00101281]], the large subunit of dimethylformamidase (DMFase), an enzyme containing a Fe+3 ion in the active site that catalyses the hydrolytic cleavage of the amide bond in N,N-dimethyl formamide. This domain is described as domain III, which adopts an alpha/beta/alpha fold, with five beta-strands that are parallel and sandwiched between alpha-helices. This domain is also found in some uncharacterised fungal sequences.</p>","llm":false,"checked":false,"updated":false}],"wikipedia":null,"literature":{"PUB00101281":{"PMID":32452120,"ISBN":null,"volume":"59","issue":"39","year":2020,"title":"A 2-Tyr-1-carboxylate Mononuclear Iron Center Forms the Active Site of a Paracoccus Dimethylformamidase.","URL":null,"raw_pages":"16961-16966","medline_journal":"Angew Chem Int Ed Engl","ISO_journal":"Angew Chem Int Ed Engl","authors":["Arya CK","Yadav S","Fine J","Casanal A","Chopra G","Ramanathan G","Vinothkumar KR","Subramanian R."],"DOI_URL":null}},"set_info":null,"overlaps_with":null,"counters":{"subfamilies":0,"domain_architectures":234,"interactions":0,"matches":4320,"pathways":0,"proteins":4303,"proteomes":2858,"sets":0,"structural_models":{"alphafold":2159},"structures":9,"taxa":4293},"entry_annotations":{"hmm":0,"logo":0,"alignment:seed":55,"alignment:full":2251},"cross_references":{},"is_llm":false,"is_reviewed_llm":false,"is_updated_llm":false,"representative_structure":null}}